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geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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connecting . GO:0034053 and GO:0080185 #18682

Closed ValWood closed 4 years ago

ValWood commented 4 years ago

GO:0034053 Definition modulation by symbiont of host defense-related programmed cell death Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. modulation by symbiont of host HR | narrow modulation by symbiont of host hypersensitive response | narrow

but these narrow synonyms have their own terms (currently unrelated) GO:0080185 effector-mediated induction of plant hypersensitive response by symbiont Definition A symbiont process whereby a molecule secreted by the symbiont activates plant effector-triggered immunity (ETI) signalling and the subsequent activation of a plant hypersensitive response to induce necrosis. In the plant, ETI involves the direct or indirect recognition of an effector protein by the host. for example through plant resistance receptor or R proteins. PMID:16497589 PMID:22241993 PMID:23411798 PMID:27641772

There are 9 annotations to GO:0034053 modulation by symbiont of host defense-related programmed cell death

Some are effectors of HR in plants and should move down to GO:0080185 Some are Effectors from human pathogens, so this term is required as a parent to the plant term.

ValWood commented 4 years ago

Hi @pgaudet did you have a question about this one? It looks straightforward?

pgaudet commented 4 years ago

Do you mean GO:0080185 effector-mediated induction of plant hypersensitive response by symbiont should be a child of

GO:0034053 modulation by symbiont of host defense-related programmed cell death

?

Thanks, Pascale

pgaudet commented 4 years ago

And, are the two synonyms on the right term ?

pgaudet commented 4 years ago

I mean those 2: modulation by symbiont of host HR | narrow modulation by symbiont of host hypersensitive response | narrow

ValWood commented 4 years ago

Do you mean GO:0080185 effector-mediated induction of plant hypersensitive response by symbiont should be a child of GO:0034053 modulation by symbiont of host defense-related programmed cell death

Yes. plant hypersensitive response is a type of programmed cell death

ValWood commented 4 years ago

I mean those 2: modulation by symbiont of host HR | narrow modulation by symbiont of host hypersensitive response | narrow

These synonyms would be better as "exact" synonyms of the more specific terms once the missing parentge is created.

pgaudet commented 4 years ago

ok

pgaudet commented 4 years ago

@ValWood I dont think I should put the 'modulation' as synonyms for 'induction'.

The parentage is OK.

I think this is all good.

Maybe you want to confirm once you can see the latest version of the ontology ?

ValWood commented 4 years ago

OK yes I will check It's getting confusing ;)

pgaudet commented 4 years ago

OK now