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geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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telomere tethering #18981

Open ValWood opened 4 years ago

ValWood commented 4 years ago

we ended up with 2 terms for "meiotic telomere tethering". I'm not sure how...we did this in detail a while back...

(note that clustering and tethering are separate steps so we should have separate processes for clustering)

But, I don't see a difference between these 2 terms

ValWood commented 4 years ago

GO:0070197 JSON meiotic attachment of telomere to nuclear envelope Biological Process

Definition (GO:0070197 GONUTS page) The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation. PMID:18818742

GO:0044821 meiotic telomere tethering at nuclear periphery Definition (GO:0044821 GONUTS page) The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle.

they sound the same don't they?

ValWood commented 4 years ago

Oh actually I think these are diffenct events. One is during prophase and one is during M-phase. I need to check this...

ValWood commented 4 years ago

There are issues. Clustering isn't part_of meiosis I. I will return to this when I have finished the paper.

pgaudet commented 3 years ago

any update ?

ValWood commented 3 years ago

There is a cool new Nature paper on this (2 days ago): https://twitter.com/promiselcooper/status/1367219412474810372 (not yet in PubMed) I'll revisit telomere tethering when this comes through the pipeline...