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Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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TIP60 Histone Acetylase Complex #2072

Closed gocentral closed 9 years ago

gocentral commented 19 years ago

Hi could I request a new component term: TIP60 Histone Acetylase Complex as a part-of child of nucleus.

Definition: A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A.

PubMed ID: 10966108

Cheers, Emily

Reported by: edimmer

Original Ticket: "geneontology/ontology-requests/2079":https://sourceforge.net/p/geneontology/ontology-requests/2079

gocentral commented 19 years ago

Logged In: YES user_id=482748

hi Emily, histone acetyltransferase complex ; GO:0000123 may be a good parent for this new term.

on a similar theme, I'd like to add the following exact synonyms in for histone acetyltransferase terms:

acetyltransferase activity ; GO:0016407 ; EC:2.3.1.-: acetylase activity histone acetyltransferase activity ; GO:0004402: histone acetylase activity histone acetyltransferase complex ; GO:0000123: histone acetylase complex histone acetyltransferase regulator activity : histone acetylase regulator activity histone acetyltransferase binding ; GO:0035035: histone acetylase binding

(see the synonym section of http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/3/1/48.html) thanks Becky

Original comment by: beckyfoulger

gocentral commented 19 years ago

Logged In: YES user_id=837342

hi Becky, Sounds good, Thanks. Emily

Original comment by: edimmer

gocentral commented 19 years ago

Original comment by: beckyfoulger

gocentral commented 19 years ago

Logged In: YES user_id=482748

new term added: TIP60 histone acetyltransferase complex ; GO:0035267

name: TIP60 histone acetyltransferase complex exact synonym: TIP60 histone acetylase complex A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. definition_reference: PMID: 10966108 definition_reference: GOA:ed

Used 'acetyltransferase' in the term name to be consistent with current histone acetyltransferase terms. Also added in the other synonyms described below.

Becky

Original comment by: beckyfoulger

gocentral commented 19 years ago

Original comment by: beckyfoulger