geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
Creative Commons Attribution 4.0 International
221 stars 40 forks source link

telomere maintenence/centromere maintenance #2103

Closed gocentral closed 9 years ago

gocentral commented 19 years ago

I have decided to add GO terms to my book chapter. I have a couple of commonly used phrases which don't map to GO

telomere function and centromere function

These phrases essentailly refer to groups of processes (not functions)

I wondered if telomere function could be a synonym of telomere maintenance but perhaps the definition of telomere maintenence should be tweaked

telomere maintenance The of maintenance ot telomere integrity? to protect chromosome ends and promote chromosome stability ?

if it is required telomere length maintenance could be a child

telomere maintenance --telomere length maintenance --telomere capping

then GONEW centromere maintenance synonym centromere function

The of maintenance of centromere associated protein complexes integrity? to ensure accurated segregation and promote chromosome stability ?

would have children

* chromatin silencing at centromere

* GONEW mitotic sister chromatid cohesion at centromere (this term has been requested previously, as there are different complexes involved in cohesion at the centromere and the arms)

* chsome separation (i.e the new term)

I haven't thought about this properly and everyone is waiting for me to go to lunch, but would somthing like this be possible?

Reported by: ValWood

Original Ticket: "geneontology/ontology-requests/2110":https://sourceforge.net/p/geneontology/ontology-requests/2110

gocentral commented 19 years ago

Logged In: YES user_id=436423

I don't think centromere (or telomere) maintenance is the same as centromere (telomere) function. You'd probably be better off referring to the component terms, although you could also mention telomere mainenance, chromosome attachment to spindles, and chromosome segregation.

For the telomere def, how would you define 'integrity'? For telomeres, the important thing is to keep them from getting too short ... I'm not seeing what the change would add ...

Original comment by: mah11

gocentral commented 19 years ago

Logged In: YES user_id=516865

Hi Midori,

no I don't think they are the same now either. and it doesn't matter because I'm not putting the terms in teh chapter at this point.

However, I think there could be a grouping term for all of the proceeses the centromere contributes to....

Original comment by: ValWood

gocentral commented 19 years ago

Logged In: YES user_id=516865

>However, I think there could be a grouping term for all of >the proceeses the centromere contributes to....

ignore this, I meant to delete it

Original comment by: ValWood

gocentral commented 19 years ago

Logged In: YES user_id=436423

so do we still need this open?

m

Original comment by: mah11

gocentral commented 19 years ago

Logged In: YES user_id=516865

...well I just remembered why I suggested the change to telomere maintenance... doesn't telomere maintenance also included things which prevent telomere ends being recognized as damaged DNA and recombining with each other (i.e not only in length regulation?)

what do you think?

but with respect to the other stuff, yes

Original comment by: ValWood

gocentral commented 19 years ago

Logged In: YES user_id=436423

well, then, how 'bout if I just change 'telomeric length' to 'telomeric length and structure' in the def?

m

Original comment by: mah11

gocentral commented 19 years ago

Logged In: YES user_id=516865

t'would do

Original comment by: ValWood

gocentral commented 19 years ago

Logged In: YES user_id=436423

OK, done

Original comment by: mah11

gocentral commented 19 years ago

Original comment by: mah11

gocentral commented 13 years ago

Original comment by: mah11