Closed Mingsenli closed 12 months ago
Hi @Mingsenli
Welcome to the GO project! Before we go ahead and create this term, would you please fill the form here: https://github.com/geneontology/helpdesk/issues/new?assignees=&labels=&template=new-member-onboarding.md&title=New+User+Onboarding
Also, have you had a chance to look at the GO annotation guidelines? This page could be useful: http://wiki.geneontology.org/index.php/Guide_to_GO_Evidence_Codes
Thanks, Pascale
Hi @Mingsenli
Did you have a chance to look at the document above?
Thanks, Pascale
I have Filled out the above form
Hi @raymond91125 Would you please look into this?
If this process is in scope, pleas use the standard definitions; usually differentiation and homeostasis are not part of the same process.
Thanks, Pascale
+[Term] +id: GO:0160122 +name: corneal epithelial cell differentiation +namespace: biological_process +def: "The process in which a relatively unspecialized cell acquires specialized features of an corneal epithelial cell, any of the cells making up an corneal epithelium." [PMID:32697979, PMID:33414365] +is_a: GO:0030855 ! epithelial cell differentiation +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22991" xsd:anyURI +created_by: rynl +creation_date: 2023-10-30T18:58:42Z
Please provide as much information as you can:
Suggested term label: corneal epithelial differentiation
Definition (free text) Limbal stem/progenitor cells residing in the basal layer of the limbus differentiate into corneal epithelial cells during homeostasis.
Reference, in format PMID:####### PMID: 33414365
Gene product name and ID to be annotated to this term EntrezID | gene name 2812 | SEPT5 63874 | ABHD4 57406 | ABHD6 25890 | ABI3BP 84448 | ABLIM2 59272 | ACE2 131 | ADH7 122622 | ADSSL1 216 | ALDH1A1 218 | ALDH3A1 221 | ALDH3B1 222 | ALDH3B2 10218 | ANGPTL7 55616 | ASAP3 285973 | ATG9B 8705 | B3GALT4 10317 | B3GALT5 573 | BAG1 576 | BAI2 27113 | BBC3 8424 | BBOX1 604 | BCL6 29760 | BLNK 90427 | BMF 149428 | BNIPL 770 | CA11 199731 | CADM4 810 | CALML3 57118 | CAMK1D 23492 | CBX7 57126 | CD177 948 | CD36 1004 | CDH6 1028 | CDKN1C 79603 | CERS4 10752 | CHL1 64581 | CLEC7A 1191 | CLU 152330 | CNTN4 27151 | CPAMD8 119587 | CPXM2 153222 | CREBRF 9244 | CRLF1 1410 | CRYAB 1471 | CST3 8722 | CTSF 51523 | CXXC5 79901 | CYBRD1 92196 | DAPL1 1628 | DBP 1634 | DCN 1672 | DEFB1 414918 | DENND6B 3338 | DNAJC4 1823 | DSC1 1828 | DSG1 1950 | EGF 2043 | EPHA4 2049 | EPHB3 79852 | EPHX3 79152 | FA2H 2167 | FABP4 220965 | FAM13C 284069 | FAM171A2 131177 | FAM3D 131583 | FAM43A 55603 | FAM46A 2192 | FBLN1 2217 | FCGRT 387758 | FIBIN 1112 | FOXN3 2548 | GAA 2593 | GAMT 9615 | GDA 54857 | GDPD2 124975 | GGT6 2697 | GJA1 2752 | GLUL 10457 | GPNMB 7107 | GPR137B 2861 | GPR37 283120 | H19 10014 | HDAC5 84525 | HOPX 3248 | HPGD 374875 | HSD11B1L 3315 | HSPB1 5654 | HTRA1 402778 | IFITM10 3481 | IGF2 3488 | IGFBP5 146433 | IL34 8850 | KAT2B 23254 | KAZN 3868 | KRT16 342574 | KRT27 3850 | KRT3 10536 | LEPREL2 29094 | LGALSL 10161 | LPAR6 22859 | LPHN1 10234 | LRRC17 66004 | LYNX1 137797 | LYPD2 130576 | LYPD6B 4094 | MAF 4118 | MAL 84557 | MAP1LC3A 4147 | MATN2 4211 | MEIS1 84709 | MGARP 26002 | MOXD1 196264 | MPZL3 4477 | MSMB 4488 | MSX2 143662 | MUC15 394263 | MUC21 79784 | MYH14 29116 | MYLIP 25791 | NGEF 2831 | NPBWR1 80896 | NPL 4883 | NPR3 1728 | NQO1 9315 | NREP 440836 | ODF3B 93145 | OLFM2 93129 | ORAI3 29943 | PADI1 5064 | PALM 89932 | PAPLN 54852 | PAQR5 5087 | PBX1 57326 | PBXIP1 5152 | PDE9A 5164 | PDK2 64065 | PERP 93210 | PGAP3 57115 | PGLYRP4 55022 | PID1 113791 | PIK3IP1 5570 | PKIB 10957 | PNRC1 5439 | POLR2J3 151742 | PPM1L 89801 | PPP1R3F 83886 | PRSS27 8000 | PSCA 442213 | PTCHD4 5764 | PTN 10966 | RAB40B 10267 | RAMP1 51195 | RAPGEFL1 56963 | RGMA 58480 | RHOU 727800 | RNF208 80352 | RNF39 6092 | ROBO2 6095 | RORA 6338 | SCNN1B 9037 | SEMA5A 80031 | SEMA6D 89778 | SERPINB11 26470 | SEZ6L2 90525 | SHF 6565 | SLC15A2 51310 | SLC22A17 63027 | SLC22A23 79085 | SLC25A23 146802 | SLC47A2 23428 | SLC7A8 285195 | SLC9A9 57152 | SLURP1 10924 | SMPDL3A 8470 | SORBS2 55553 | SOX6 6678 | SPARC 11005 | SPINK5 84651 | SPINK7 10417 | SPON2 6707 | SPRR3 55304 | SPTLC3 222183 | SRRM3 55959 | SULF2 9145 | SYNGR1 6920 | TCEA3 6948 | TCN2 7045 | TGFBI 7077 | TIMP2 257000 | TINCR 7089 | TLE2 7100 | TLR5 7108 | TM7SF2 55273 | TMEM100 51754 | TMEM8B 84000 | TMPRSS13 94241 | TP53INP1 58476 | TP53INP2 79090 | TRAPPC6A 55521 | TRIM36 1831 | TSC22D3 25809 | TTLL1 10628 | TXNIP 10791 | VAMP5 57216 | VANGL2 10451 | VAV3 5212 | VIT 155382 | VPS37D 64856 | VWA1 65268 | WNK2 54361 | WNT4 83719 | YPEL3 201501 | ZBTB7C 140467 | ZNF358 168544 | ZNF467 4582 | MUC1 4585 | MUC4 94025 | MUC16 192666 | KRT24 3859 | KRT12 9518 | GDF15 655 | BMP7 2296 | FOXC1 9314 | KLF4 3490 | IGFBP7 3486 | IGFBP3
Parent term(s) biological_process
Children terms (if applicable) Should any existing terms that should be moved underneath this new proposed term?
Synonyms (please specify, EXACT, BROAD, NARROW or RELATED) differentiation of corneal epithelial cells
Cross-references
For enzymes, please provide RHEA and/or EC numbers.
Can also provide MetaCyc, KEGG, Wikipedia, and other links.
Any other information