Closed pgaudet closed 2 years ago
References: Type I (alpha): PMID:32733001, PMID:19802576, PMID:32464097, PMID:33097660, PMID:26712804 Type 2: (gamma): PMID:28901902 Type 3 (lambda): PMID:32464097
See also: https://viralzone.expasy.org/883
Also created the missing 'normal' terms and changed 'interferon-gamma' to Type II interferon in all GO terms.
+[Term] +id: GO:0140886 +name: suppression by virus of host interferon-mediated signaling pathway +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interferon-mediated signaling in the host organism." [PMID:33097660] +synonym: "inhibition of host interferon signaling pathway by virus" RELATED [] +synonym: "negative regulation by virus of host interferon-mediated signaling pathway" EXACT [] +synonym: "suppression by virus of host IFN-mediated signaling pathway" EXACT [] +synonym: "suppression by virus of host interferon-mediated signalling pathway" EXACT [] +is_a: GO:0039503 ! suppression by virus of host innate immune response +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0140888 ! interferon-mediated signaling pathway +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/23647 xsd:anyURI +created_by: pg +creation_date: 2022-07-08T09:23:17Z + +[Term] +id: GO:0140888 +name: interferon-mediated signaling pathway +namespace: biological_process +def: "The series of molecular signals initiated by type II interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type II interferon is also known as interferon-gamma." [GOC:add, GOC:dph, GOC:signaling, PMID:32464097] +synonym: "interferon signaling pathway" EXACT [] +synonym: "interferon-activated signaling pathway" EXACT [GOC:signaling] +is_a: GO:0019221 ! cytokine-mediated signaling pathway +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/23647 xsd:anyURI +created_by: pg +creation_date: 2022-07-08T09:36:25Z
+ +[Term] +id: GO:0140885 +name: suppression by virus of host type III interferon-mediated signaling pathway +namespace: biological_process +def: "Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type III interferon-mediated signalin g in the host organism. Type III interferon is also known as interferon-lambda." [PMID:32464097] +synonym: "negative regulation by virus of host type III interferon-mediated signaling pathway" EXACT [] +synonym: "suppression by virus of host type III IFN-mediated signaling pathway" EXACT [] +synonym: "suppression by virus of host type III interferon-mediated signalling pathway" EXACT [] +intersection_of: GO:0019054 ! modulation by virus of host cellular process +intersection_of: negatively_regulates GO:0038196 ! type III interferon-mediated signaling pathway +property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/23647 xsd:anyURI +created_by: pg +creation_date: 2022-07-08T09:20:57Z
Hello,
The @geneontology/multiorganism-working-group would like to create a sibling term to 'GO:0039502 suppression by virus of host type I interferon-mediated signaling pathway', suppression by virus of host type I Iinterferon-mediated signaling pathway'
and a parent term, 'suppression by virus of host interferon-mediated signaling pathway'
Thanks, Pascale