Term merge: protection from non-homologous end joining at telomere GO:0031848 -> telomere capping GO:0016233

[Antonialock]

• Term to be merged: Provide GO ID and term label protection from non-homologous end joining at telomere GO:0031848

• Which term do you propose this term merge into? Provide GO ID and term label telomere capping GO:0016233

• Reason for merge

to me it sounds like protection from non-homologous end joining at telomere A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.

is one "job" of elomere capping telomere capping is defined as A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.

telomere protection has (an odd?) connection to DNA damage response

• Reference(s) PMID:nnnnnn

• Any other information @ValWood @RLovering

[ValWood]

I don't see any obvious difference between these processes.

[ValWood]

telomere capping is just "what the cap does" telomere cap complex (GO:0000782) but "telomere protection " is a better way of describing the process.

[RLovering]

There are 2 child terms for telomere capping:

GO ID name	% proteins with EXP evidence	number of proteins with EXP evidence
GO:0016233 telomere capping	81.67	49
GO:0031848 protection from non-homologous end joining at telomere	23.33	14
GO:0031860 telomeric 3' overhang formation	11.67	7

I agree that the is_a parent for protection from non-homologous end joining at telomere should be telomere maintenance not the DNA damage term.

Is it useful to group proteins involved in telomeric 3' overhang formation separately from protection from non-homologous end joining at telomere? if not then I agree merge both terms into telomere capping (renaming telomere protection seems like a good idea).