Consider renaming GO:0036335 to 'intestinal crypt stem cell homeostasis'

[ghost]

From https://github.com/obophenotype/cell-ontology/issues/79:

From @addiehl's comment:

"I think the CL class 'intestinal crypt stem cell' (CL:0002250) is the appropriate choice for the required logical definition of GO:0036335, based on a simple Google search for "intestinal stem cell" and reading what I found. Arguably GO:0036335 should be renamed "intestinal crypt stem cell homeostasis," but I will leave that to GO to ponder."

[raymond91125]

I believe Drosophila intestine does not have crypt but does have stem cells. For the sake of keeping this term more generally (taxon-wise) applicable, we probably should not define it using 'intestinal crypt stem cell'.

[ghost]

Thank you for the insight, @raymond91125. If a reference can be identified to justify whether to close the ticket or make an edit, can that be provided?

CC @gouttegd

[gouttegd]

Indeed, there are no crypts in the Drosophila midgut – though people sometimes use that term even in flies, by analogy with the mammalian gut.

For reference, you may have a look at Figure 2 in Jiang and Edgar, 2012 (PMID:22608824).

So if intestinal stem cell homeostasis is intended to also apply to Drosophila (which seems to be the case, I can see that it has been used to annotate fly genes), I agree that it should probably not be renamed to mention “crypt” in the label – though maybe this could be added as a synonym?

[ghost]

Thank you for sharing your expertise, @gouttegd!

[gouttegd]

By the way, I meant Figure 1 in the Jiang and Edgar paper, sorry.

[raymond91125]

I can add a 'narrow' synonym "intestinal crypt stem cell homeostasis" if that's helpful. Also PMID:22608824 is a good ref to add. Thanks.