BP for calcium ion importer

[ValWood]

I have 3 term choices

@pgaudet what is the preferred solution? Can I add Calcium ion import across plasma membrane into cytosol (or does import imply import into cell- this isn't necessarily how it is used, I see it used also for ER->cytosol)

[pgaudet]

There are a lot of inconsistencies in that branch.

To me, just 'import' doesn't mean anything, it could be 'import into cell', 'import into ER', vacuole etc

I thought for a while that 'import across the plasma membrane' was better for bacteria and plants, because many of the transporters are at the plasma membrane, but maybe the best is 'import into cell'

'calcium import into cytosol' is not clear enough, it can mean from the extracellular medium or from intracellular stores.

Specifically for calcium, there seems to be way too many terms already. Should we look at that on one of our calls?

Pascale

[ValWood]

Yes, no hurry I just want to annotate them consistently.

[ValWood]

I will add the term I needed calcium ion import across plasma membrane

[ValWood]

calcium ion import across plasma membrane exists but does not have the import parents listed above

[ValWood]

Calcium import across plasma membrane should be a child of calcium ion import and calcium ion import into cytosol

(these two terms should perhaps be 'transmembrane' terms but that can be looking into later. \

I will add the missing parent here to suppress summarize the annotation better, and make the specific term findable

[ValWood]

ACTION: GO:0098703 is_a GO:0070509 GO:0098703 is_a GO:1902656

[pgaudet]

I would lean towards obsoleting GO:0070509 calcium ion import (and all "import" terms that dont mention where a substrate is imported), as well as 'GO:1902656 calcium ion import into cytosol', since that includs both import from extracellular and import from calcium stores.

Most likely the term curators were trying to use was calcium import across plasma membrane.

[ValWood]

I agree, I only added these to fix a short term problem of function predictions. But all substrate specific transport needs review/merge. I was worried it might take longer than the next batch of function predictions ;) Plus it's easier to do the obsolete and replace if the child terms are in the correct place (unless these had been isolated because the obsoletion was already in progress?)