geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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Proposal to deal with GO:0044403 biological process involved in symbiotic interaction #27736

Open pgaudet opened 2 months ago

pgaudet commented 2 months ago

@pmasson55 proposes that we change definition of the following terms to allow annotation of host proteins:

'biological process involved in interaction with host' http://purl.obolibrary.org/obo/GO_0051701 'biological process involved in interaction with symbiont' http://purl.obolibrary.org/obo/GO_0051702 'biological process involved in symbiotic interaction' http://purl.obolibrary.org/obo/GO_0044403 'biological process involved in interspecies interaction between organisms' http://purl.obolibrary.org/obo/GO_0044419 'biological process involved in intraspecies interaction between organisms' http://purl.obolibrary.org/obo/GO_0051703 'regulation of biological process involved in symbiotic interaction' http://purl.obolibrary.org/obo/GO_0043903

& some children like: 'migration in host' 'acquisition of nutrients from host' 'adhesion of symbiont to host' 'exit from host cell' 'symbiont entry into host' 'symbiont intracellular protein transport in host' 'symbiont-mediated killing of host cell' 'translocation of molecules into host'

pgaudet commented 1 month ago

Call with @genegodbold Maybe this could be organized like this:

. interspecies interaction .. symbiont-mediated modulation of host process .. venom-mediated modulation of process in another organism .. host-mediated modulation of symbiont process .. symbiont intracellular protein transport in host {host + symbiont proteins} .. viral translation {host + symbiont proteins} .. migration in host {host + symbiont proteins} .. killing of cells of another organism ... neutrophil-mediated cell killing

pgaudet commented 3 days ago

Examples: GO:0046761 viral budding from plasma membrane - check mammalian proteins annotated to this; do we want these host proteins to be annotated to this process, or only symbiont proteins?