Open ValWood opened 1 month ago
Not sure I understand the request for immunological synapse formation - it's already inheriting a constraint to Vertebrata?
Weird, I checked them, but these have been sitting on my desktop for a week since then. EIther it has just. been added, or I made a mistake. I'll scrub that one.
Oh I see, the request is for "immunological synapse" and I was just noting the existing GO:0001771 immunological synapse formation Only in Taxon 7742 Vertebrata
Yes, ideally we would have a CC for the synapse and place the TC there
Sarcollema TC will be inherited from CL next release:
Please provide as much information as you can:
MOre taxon constraints hanging around on my desktop:
apical plasma membrane urothelial plaque A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array. PMID:21468280 PMID:21887288
urothelial superficial (umbrella) cells are vertebrae specific
====
cell trailing edge membrane The portion of the plasma membrane surrounding the trailing edge of a motile cell.
leading edge membrane The portion of the plasma membrane surrounding the leading edge of a motile cel
I think usually we just have never in fungo for motile cells ?
=====
immunological synapse An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. PMID:11244041 PMID:11376300
GO:0001771 immunological synapse formation Only in Taxon 7742 Vertebrata
=====
orthogonal array Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels). PMID:22718347
0 annotations - obsoletion might be better?
=====
phagocytic cup An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome. PMID:10358769
CC "phagosome" does not exist but GO:0045335 phagocytic vesicle Never in Taxon 4751 Fungi GO:0045335 phagocytic vesicle Only in Taxon 131567 cellular organisms
===== sarcolemma The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.