Missing parent: GO:0001576 globoside biosynthetic process

geneontology / go-ontology

Source ontology files for the Gene Ontology

http://geneontology.org/page/download-ontology

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Open ValWood opened 2 weeks ago

ValWood commented 2 weeks ago

GO:0001576 globoside biosynthetic process

The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).

If this is a valid classification it should have is_a ceramide biosynthetic process, since it is defined as a ceramide

ValWood commented 2 weeks ago

may be a definition proble. Glycosphingolipids are derived from ceramides

pgaudet commented 2 weeks ago

This is a ChEBI issue. Please open a ticket there.

ValWood commented 2 weeks ago

Is globoside definitely a ceramine, though?

deustp01 commented 2 weeks ago

A quick Google search shows that:

Globosides are a type of glycosphingolipid (GSL) made up of a ceramide backbone, and a terminal oligosaccharide.
A ceramide is composed of sphingosine and a fatty acid joined by an amide bond.
Sphingosine (2-amino-4-trans-octadecene-1,3-diol) is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain.

So a ceramide is a part of a globoside in the same way that adenine is a part of NAD.

ValWood commented 2 weeks ago

OK, I will alter the definiton.