Specialized extracellular matrix(requested add term #29265)
Reason for changing parent
To better describe the general understanding of ECM components, keep the main structure of extracellular matrix of connective tissues (dermis, cartilage, bone) in metazoan as the general physiological component. The extracellular matrix contains three types of ECM: the interstitial ECM, basement membrane ECM, and the interface that anchored them together.
Reference, in format PMID:
(REQUIRED)
Add new terms as child term
Add new child term of Basement membrane (GO: 0005604)
collagenous component of basement membrane
child term: Basement membrane hexagonal network (GO:0098646)(requested name change), Chicken wire-like network(requested add term )
non-collagenous component of basement membrane
child term: Basement membrane gel phase(requested add term #29268), Basement membrane solid phase(To be build)
Add new child term of Interstitial matrix (GO:0005614)
non-collagenous component of interstitial matrix
child term: Interstitial matrix gel phase(requested add term #29269 ), Interstitial matrix solid phase(To be build)
child term of Basement membrane/interstitial matrix interface
Collagen beaded filaments (GO:0098647), Anchoring collagen complex (GO:0098648)(requested name change)
Reason for adding new terms
The collagenous and non-collagenous part of ECM has distinct function and components, adding new terms to better annotate and group the component of ECM.
Reference
PMID: 39223427 : Naba A. Mechanisms of assembly and remodelling of the extracellular matrix. Nat Rev Mol Cell Biol. 2024 Sep 2. doi: 10.1038/s41580-024-00767-3.
Change term parent
The 4 direct child terms of extracellular matrix (GO:0031012) as follow:
Reason for changing parent To better describe the general understanding of ECM components, keep the main structure of extracellular matrix of connective tissues (dermis, cartilage, bone) in metazoan as the general physiological component. The extracellular matrix contains three types of ECM: the interstitial ECM, basement membrane ECM, and the interface that anchored them together.
Reference, in format PMID: (REQUIRED)
Add new terms as child term
Add new child term of Basement membrane (GO: 0005604)
Add new child term of Interstitial matrix (GO:0005614)
child term of Basement membrane/interstitial matrix interface
Reason for adding new terms The collagenous and non-collagenous part of ECM has distinct function and components, adding new terms to better annotate and group the component of ECM.
Reference PMID: 39223427 : Naba A. Mechanisms of assembly and remodelling of the extracellular matrix. Nat Rev Mol Cell Biol. 2024 Sep 2. doi: 10.1038/s41580-024-00767-3.
Other information
Framework in slide page 1: https://docs.google.com/presentation/d/1CfY-qBrZLK-7TBR8GB9V87uYdBdPmeg9/edit?usp=sharing&ouid=109267399050361021326&rtpof=true&sd=true