ntr: astral microtubule stability

[gocentral]

child of astral microtubule organization and biogenesis; GOid=GO:0030953

or do I mean 'astral microtuble stabilization?'.

I'm not up to speed on the distinction between attribute/process used for stability/stabilization.

PMID: 16951255

Reported by: ValWood

Original Ticket: "geneontology/ontology-requests/3883":https://sourceforge.net/p/geneontology/ontology-requests/3883

[gocentral]

Logged In: YES user_id=516865 Originator: YES

for the same paper I need

cytoplasmic astral microtubule organization and biognensis --cytoplasmic astral microtubule stabilization ----regulation of ctoplasmic astral microtubule stabilizationm (+ve and -ve)

also there is an axonemal microtubule stabilization

but no 'microtubule stabilization'

Original comment by: ValWood

[gocentral]

Logged In: YES user_id=436423 Originator: NO

added negative regulation of astral microtubule depolymerization GO:0032932, with 'astral microtubule stabilization' as an exact synonym

Stability is an attribute; stabilization is a process. In theory, we could either have 'regulation of stability' terms under regulation of biological quality or 'regulation of stabilization' terms under regulation of biological process. In practice, for microtubules we've opted for 'negative regulation of depolymerization' because that's essentially what MT stabilization is. (Tangential note: the same is true for 'RNA stabilization' according to the defs, so those terms could be renamed or given 'structured synonyms' if we feel like it.)

m

Original comment by: mah11

[gocentral]

• milestone: --> 224410
• status: open --> closed-accepted

Original comment by: mah11

[gocentral]

• milestone: 224410 --> PomBase

Original comment by: mah11