gocentral
commented
16 years ago Logged In: YES user_id=436423 Originator: NO
added squalene cyclase activity GO:0034072 tetrahymanol cyclase activity GO:0034073 marneral synthase activity GO:0034074 arabidiol synthase activity GO:0034075 cucurbitadienol synthase activity GO:0034076
synonyms and other stuff done as requested
Original comment by: mah11
Hello,
PMID: 18033581 is my basis for much of this.
"squalene:hopene cyclase activity" as EXACT synonym for GO:0051007.
"oxidosqualene:lanosterol cyclase activity" as EXACT for GO:0000250.
"oxidosqualene:cycloartenol cyclase activity" as EXACT for GO:0016871.
"oxidosqualene:beta-amyrin cyclase activity" as EXACT for GO:0042300.
"oxidosqualene:lupeol cyclase activity" as EXACT for GO:0042299.
New terms:
name: squalene cyclase activity def: "Catalysis of the reaction: squalene = triterpene." is_a: GO:0009975 ! cyclase activity
(GO:0051007 then should move from being a cyclase activity to being a squalene cyclase activity.)
name: tetrahymanol cyclase activity def: "Catalysis of the reaction: squalene = tetrahymanol (CHEBI:9493)." synonym: "squalene:tetrahymanol cyclase activity" EXACT [] is_a: squalene cyclase activity
name: marneral synthase activity def: "Catalysis of the reaction: oxidosqualene = marneral." [PMID:16425307] synonym: "oxidosqualene:marneral cyclase activity" EXACT [] is_a: GO:0031559 ! oxidosqualene cyclase activity
(Marneral is in Scheme S2 of the supplementary data for the relevant paper here: http://www.wiley-vch.de/contents/jc\_2002/2006/z503420\_s.pdf)
name: arabidiol synthase activity def: "Catalysis of the reaction: oxidosqualene = arabidiol ((3S,13R,14R)-malabarica-17E,21-dien-3β,14-diol)." synonym: "oxidosqualene:arabidiol cyclase activity" EXACT [] is_a: GO:0031559 ! oxidosqualene cyclase activity
name: cucurbitadienol synthase activity def: "Catalysis of the reaction: oxidosqualene = cucurbitadienol." [http://beta.uniprot.org/uniprot/Q6BE24] is_a: GO:0031559 ! oxidosqualene cyclase activity
I think that's enough for now.
best wishes, Colin.
Reported by: batchelorc
Original Ticket: "geneontology/ontology-requests/4701":https://sourceforge.net/p/geneontology/ontology-requests/4701