geneontology / go-ontology

Source ontology files for the Gene Ontology
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NTR: innervation #4859

Closed gocentral closed 9 years ago

gocentral commented 16 years ago

This came up on the annotation list months ago and I failed to follow-up with a sf request...

I don't think there is a term that adequately covers the process of innervation. I think of innervation as the process of supplying nerves to a target tissue and making functional connections with that tissue.

We have nerve maturation - but that doesn't seem to address the tissue that the nerve contacts.

We also have axonogenesis and synaptogenesis which both seem to be part of innervation rather than synonomous with it.

Susan

Reported by: stweedie

Original Ticket: "geneontology/ontology-requests/4874":https://sourceforge.net/p/geneontology/ontology-requests/4874

gocentral commented 16 years ago

Logged In: YES user_id=1515568 Originator: YES

George would also like the following children of innervation so he can decompose these molecular phenotype terms.

I wasn't sure whether to add them all as separate sf items at this stage but I thought it may be useful to have them all together with the parental request for now. One issue to consider is that some of these terms are named on the basis of the target tissue/cells being innervated and other are named for the nerve/neuron that is innervating which is potentially a bit confusing.

abnormal motor neuron innervation !TERM request: motor neuron innervation abnormal muscle innervation !TERM request: muscle innervation abnormal Purkinje cell innervation !TERM request: Purkinje cell innervation abnormal enteric cholinergic innervation !TERM request: enteric cholinergic innervation hyperinnervation of hair guard cells !TERM request: hair guard cell innervation hyperinnervation of hair-down cells !TERM request: hair-down cell innervation hyperinnervation of hair-tylotrich cells !TERM request: hair-tylotrich cell innervation abnormal sensory neuron innervation !TERM request: sensory neuron innervation abnormal cochlear OHC afferent innervation !TERM request: cochlear outer hair cell afferent innervation abnormal cochlear OHC efferent innervation !TERM request: cochlear outer hair cell efferent innervation abnormal cochlear IHC efferent innervation !TERM request: cochlear inner hair cell efferent innervation abnormal cochlear IHC afferent innervation !TERM request: cochlear inner hair cell afferent innervation hyperinnervation of Merkel's receptor !TERM request: Merkel's receptor innervation hyperinnervation of Meissner's corpuscle !TERM request: Meissner's corpuscle innervation abnormal optic nerve innervation !TERM request: optic nerve innervation neurogenic bladder !TERM request: central nervous system innervation neurogenic bladder !TERM request: peripheral nervous system innervation

Original comment by: stweedie

gocentral commented 16 years ago

Original comment by: ukemi

gocentral commented 15 years ago

Added:

innervation ; GO:00060384 axonogenesis involved in innervation ; GO:00060385 synaptogenesis involved in innervation ; GO:00060386

Original comment by: ukemi

gocentral commented 15 years ago

Original comment by: ukemi