geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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platelet binding terms #5462

Closed gocentral closed 9 years ago

gocentral commented 16 years ago

Hi,

I'm not sure about these terms, as they are cell type specific.

NT: platelet cell surface binding Defn: Interacting selectively with any component on the surface of platelet. is_a: GO:0043499 eukaryotic cell surface binding

NT: activated platelet cell surface binding Defn: Interacting selectively with any component on the surface of an activated platelet. is_a: platelet cell surface binding

NT: resting platelet cell surface binding Defn: Interacting selectively with any component on the surface of a resting platelet. is_a: platelet cell surface binding

Any comments, advice etc much appreciated!

Thanks, Varsha

Reported by: vkhodiyar

Original Ticket: "geneontology/ontology-requests/5480":https://sourceforge.net/p/geneontology/ontology-requests/5480

gocentral commented 16 years ago

I really dislike all of the cell surface binding terms, because they don't identify any specific thing that's being bound. Different gene products might bind different molecules on the surface of any given cell, and "cell surface binding" doesn't let you conclude anything about what the gene products might have in common.

m

Original comment by: mah11

gocentral commented 16 years ago

Hi Midori,

I can see your point; but as we do have GO:0043499 eukaryotic cell surface binding, I will make these annotations to that term instead, or were you planning to obsolete this term?

Thanks, V

Original comment by: vkhodiyar

gocentral commented 16 years ago

I would like to be able to make GO:0043499 obsolete, but I don't think anything will happen any time soon (not least simply because we have so much else to do). If we ever do make it obsolete, we'll recommend something to use instead; you might as well use GO:0043499 in the meantime.

When column 16 becomes available in the annotation file, you can put the Cell Ontology ID for platelet (CL:0000233) there.

Original comment by: mah11

gocentral commented 16 years ago

Will do, thanks Midori

Original comment by: vkhodiyar

gocentral commented 16 years ago

Original comment by: vkhodiyar