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teichoic acid terms #5827

Closed gocentral closed 9 years ago

gocentral commented 15 years ago

Teichoic acid terms Teichoic acids are found in the cell walls of gram-positive bacteria and are of two types, wall teichoic acid and lipoteichoic acid. The two types have related but distinct chemical structures and rely on separate pathways of biosynthesis. Lipoteichoic acid is of particular interest because of its proinflammatory properties.

1) [Term] id: GO:NewTer1 name: response to lipoteichoic acid def: "A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:16020688, PMID:14665680] synonym: "response to LTA" EXACT is_a: GO:0002237 ! response to molecule of bacterial origin

2) [Term] id: GO:NewTer2 name: detection of lipoteichoic acid def: "The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:16020688, PMID:14665680] synonym: "detection of LTA" EXACT is_a: GO:0032490 ! detection of molecule of bacterial origin is_a: GO:NewTer1 ! response to lipoteichoic acid

3) [Term] id: GO:NewTer3 name: teichoic acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues." [GOC:add, PMID:14665680] synonym: teichoic acid breakdown synonym: teichoic acid catabolism synonym: teichoic acid degradation is_a: GO:0046374 ! teichoic acid metabolic process

4) [Term] id: GO:NewTer4 name: lipoteichoic acid metabolic process def: "The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:16020688, PMID:14665680] synonym: "lipoteichoic acid metabolism" EXACT synonym: "LTA metabolic process" EXACT is_a: GO:0046374 ! teichoic acid metabolic process

5) [Term] id: GO:NewTer5 name: lipoteichoic acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:16020688, PMID:14665680] synonym: "lipoteichoic acid biosynthesis" EXACT synonym: "LTA biosynthetic process" EXACT synonym: "lipoteichoic acid anabolism" EXACT Synonym: "lipoteichoic acid biosynthesis" EXACT Synonym: "lipoteichoic acid formation" EXACT Synonym: "lipoteichoic acid synthesis" EXACT is_a: GO:0019350 ! teichoic acid biosynthetic process is_a: GO:NewTer4 ! lipoteichoic acid metabolic process

6) [Term] id: GO:NewTer6 name: lipoteichoic acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor." [GOC:add, PMID:14665680] synonym: "lipoteichoic acid breakdown" EXACT synonym: "lipoteichoic acid catabolism" EXACT synonym: "lipoteichoic acid degradation" EXACT is_a: GO:0046374 ! teichoic acid metabolic process is_a: GO:NewTer4 ! lipoteichoic acid metabolic process

7) [Term] id: GO:NewTer7 name: wall teichoic acid metabolic process def: "The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:16020688, PMID:14665680] synonym: "wall teichoic acid metabolism" EXACT synonym: "WTA metabolic process" EXACT is_a: GO:0046374 ! teichoic acid metabolic process

8) [Term] id: GO:NewTer8 name: wall teichoic acid biosynthetic process def: "The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:16020688, PMID:14665680] synonym: "wall teichoic acid biosynthesis" EXACT synonym: "WTA biosynthetic process" EXACT synonym: "wall teichoic acid anabolism" EXACT Synonym: "wall teichoic acid biosynthesis" EXACT Synonym: "wall teichoic acid formation" EXACT Synonym: "wall teichoic acid synthesis" EXACT is_a: GO:0019350 ! teichoic acid biosynthetic process is_a: GO:NewTer7 ! wall teichoic acid metabolic process

9) [Term] id: GO:NewTer9 name: wall teichoic acid catabolic process def: "The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan." [GOC:add, PMID:14665680] synonym: "wall teichoic acid breakdown" EXACT synonym: "wall teichoic acid catabolism" EXACT synonym: "wall teichoic acid degradation" EXACT is_a: GO:0046374 ! teichoic acid metabolic process is_a: GO:NewTer7 ! wall teichoic acid metabolic process

10) [Term] id: GO:NewTe10 name: teichoic acid D-alanylation def: The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid. [GOC:add, PMID:16020688, PMID:14665680] synonym: "teichoic acid alanylation" EXACT is_a: GO:0019350 ! teichoic acid biosynthetic process

Thanks,

Alex (IDO)

Reported by: addiehl

Original Ticket: "geneontology/ontology-requests/5845":https://sourceforge.net/p/geneontology/ontology-requests/5845

gocentral commented 15 years ago

added response to lipoteichoic acid GO:0070391 detection of lipoteichoic acid GO:0070392 teichoic acid catabolic process GO:0070393 lipoteichoic acid metabolic process GO:0070394 lipoteichoic acid biosynthetic process GO:0070395 lipoteichoic acid catabolic process GO:0070396 wall teichoic acid metabolic process GO:0070397 wall teichoic acid biosynthetic process GO:0070398 wall teichoic acid catabolic process GO:0070399 teichoic acid D-alanylation GO:0070400

Original comment by: mah11

gocentral commented 15 years ago

Original comment by: mah11

gocentral commented 15 years ago

note: for GO:0070395, I had to change the scope of the 'LTA biosynthetic process' to BROAD because in GO:0042109 LTA is used as an abbreviation for lymphotoxin A.

Original comment by: mah11

gocentral commented 15 years ago

Midori,

Thanks for entering the terms and spotting the synonym scope problem.

-- Alex

Original comment by: addiehl

gocentral commented 15 years ago

thanks to the awesome power of the OE verification Name Redundancy check

Original comment by: mah11