HMP-PP diphosphatase activity

[gocentral]

GO:00new 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity; syn HMP-PP phosphatase ; syn HMP-PP pyrophosphatase Def: 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + water = 2-methyl-4-amino-5-hydroxymethyl pyrimidine monophosphate + Pi is_a: GO:0017110 I am going by the following recommendation for naming:http://www.chem.qmul.ac.uk/iubmb/newsletter/2004/item4.html "Where two phosphoric residues are linked by oxygen atoms, the term "diphosphate" is recommended, rather than pyrophosphate, as in "adenosine diphosphate". Note that "diphosphate" should not be used when two independent phosphoric residues are substituted on different oxygen atoms in a single compound. In this case, the appropriate prefix is "bis", as in "fructose 1,6-bis(phosphate)". By extension of this principle, for example, the enzyme name "prenyl-diphosphatase" replaces "prenyl-pyrophosphatase". "

You can assign it to me; this is for Brenlely

Reported by: hdrabkin

Original Ticket: geneontology/ontology-requests/6221

[gocentral]

looks fine; thanks

Original comment by: mah11

[gocentral]

• assigned_to: nobody --> hjdrabkin

Original comment by: mah11

[gocentral]

Reaction showing HMP-PP

Original comment by: hdrabkin

[gocentral]

Added GO:0002145, but made child of GO:0016462, pyrophosphatase activity, since HMP-PP appears not to be attached to a sugar (figure attached).

Original comment by: hdrabkin

[gocentral]

• status: open --> closed-accepted

Original comment by: mah11