gocentral
commented
15 years ago added Yb body GO:0070725
There's some precedent for adding terms at this early stage of CC characterization, e.g. some of the children of 'nuclear body'. I think you're right to be cautious and not yet count it as a GO organelle. It may turn out to be a protein complex or a protein-RNA complex.
(as a formality I'll leave this open until tomorrow)
m
Original comment by: mah11
PMID: 19433453 (entitled "The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster.") describes a new 'organelle' that is distinct from other known cytoplasmic structures. I'm not sure if this merits a new term or not. This is the first paper to describe it and they don't know much about it other that the fact it contains Yb protein. Although they call it an organelle I think I'd class it as a cytoplasmic part as I don't think they have shown that it is an 'organized structure of distinctive morphology and function.'
suggested new term: name: Yb body namespace: cellular_component def: "An electron-dense sphere of around 1.5 micron diameter containing Yb protein found in the cytoplasm of somatic cells of ovary and testis. There are one to two Yb bodies per cell." [PMID:19433453] is_a: GO:0044444 ! cytoplasmic part
Thanks, Susan
Reported by: stweedie
Original Ticket: geneontology/ontology-requests/6239