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Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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Problem with definition of dendrite #6359

Closed gocentral closed 9 years ago

gocentral commented 15 years ago

This is the current definition of dendrite:

"A branching protoplasmic process of a neuron that receive and integrate signals coming from axons of other neurons, and convey the resulting signal to the body of the cell."

The last clause may be problematic as, for monopolar neurons that branch into axon and dendrite, the signal may be conveyed from dendrite to axon, but not via the cell body. This is the case for (many) insect inter-neurons.

Reported by: dosumis

Original Ticket: geneontology/ontology-requests/6378

gocentral commented 15 years ago

On the basis of (Google's preview of) 'Clinical Neuroanatomy' ISBN~ 0781794277 I propose changing the dendrite definition to:

A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.

Will that solve the problem here? And would any futher adjustments be necessary for SF 2835466?

m

Original comment by: mah11

gocentral commented 15 years ago

Original comment by: mah11

gocentral commented 15 years ago

p.s. "receives and integrates signals from other neurons" can be changed to "receives and integrates signals from sensory stimuli or other neurons " if necessary to account for SF 2835466

Original comment by: mah11

gocentral commented 14 years ago

Hi Midori,

Sorry for not commenting earlier. Your suggestions sound good to me. So, just to confirm, the new def will read:

"A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body."

Cheers, David

Original comment by: dosumis

gocentral commented 14 years ago

Hi David,

Yes, that definition is correct. I should get the update in today.

midori

Original comment by: mah11

gocentral commented 14 years ago

new definition now in place :)

Original comment by: mah11

gocentral commented 14 years ago

Original comment by: mah11