MP: conjugation

[gocentral]

Can conjugation with cellular fusion have the parent cell differentiation?

](I may have asked this before but if so i'm not sure why not)

Val

Reported by: ValWood

Original Ticket: geneontology/ontology-requests/6389

[gocentral]

I think it's because ontology developers collectively decided that conjugation (any type) is a multi-organism process -- i.e. the whole process is defined as encompassing what happens to both cells/organisms. Cell differentiation is a cellular process, so making it a parent of conjugation (or any is_a child of conjugation) would be a disjoint violation.

n

Original comment by: mah11

[gocentral]

Oh yes i forgot.

In this case perhaps the child term steps preceeding cell-cell fusion could have the cell differention parent? response to pheromone during conjugation woith cellula fusion adaptation.....

Original comment by: ValWood

[gocentral]

Do they fit the cell differentiation definition?

"The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate."

Original comment by: mah11

[gocentral]

well perhaps not, but would any fungal differentiation fit this definition? it seems too narrow....

Original comment by: ValWood

[gocentral]

I think spore formation, especially in multicellular fungi, and hyphal cell formation (a la filamentous fungi) fit the existing def of cell differentiation. I'm not so sure about conjugation, or single-celled yeasties generally.

m

Original comment by: mah11

[gocentral]

OK, I agree close Val

Original comment by: ValWood

[gocentral]

• status: open --> closed-works-for-me

Original comment by: mah11

[gocentral]

• milestone: --> PomBase

Original comment by: mah11