hematopoietic cell proliferation

geneontology / go-ontology

Source ontology files for the Gene Ontology

http://geneontology.org/page/download-ontology

Creative Commons Attribution 4.0 International

223 stars 40 forks source link

hematopoietic cell proliferation #6771

Closed gocentral closed 9 years ago

gocentral commented 14 years ago

Hi, would it be possible to create a GO term hematopoietic cell proliferation (based on data from PubMed=15889140), that would link GO:0008283 cell proliferation to GO:0030097 hemopoiesis.

Definition: The multiplication or reproduction of hematopoietic stem cell, resulting in the expansion of a hematopoietic cell population. Hematopoietic cells will differentiate into myeloid and lymphoid cells.

Thanks for your help, Lionel Breuza.

Reported by: lbreuza

Original Ticket: geneontology/ontology-requests/6791

gocentral commented 14 years ago

From the paper, and my (admittedly rudimentary) understanding of hematopoiesis, it's the hematopoietic stem cells that proliferate, so we should use "hemopoietic stem cell" (exact synonym: "hematopoietic stem cell") in the term name and definition consistently.

Apart from that, I don't see any problem with adding a new term. I've emailed Alex Diehl at MGI for his comments, especially on parentage.

midori

Original comment by: mah11

gocentral commented 14 years ago

Hi, yes, I agree with your suggestions. Thanks, Lionel.

Original comment by: lbreuza

gocentral commented 14 years ago

I agree with Midori's suggestion of "hematopoietic stem cell proliferation" and her placement of the term.

Thanks,

Alex

Original comment by: addiehl

gocentral commented 14 years ago

added hemopoietic stem cell proliferation GO:0071425

Original comment by: mah11

gocentral commented 14 years ago

assigned_to: nobody --> gomidori
status: open --> closed-accepted

Original comment by: mah11