Closed gocentral closed 9 years ago
I'm not quite sufficiently up to speed with the development-context meaning of "formation", especially how it differs from "assembly", but if there is a difference, then we have a ton of synonyms to remove or change scope, not only for assembly terms but also for biosynthesis.
The placement of cellular component [x] under anatomical [x] was done to death -- we spent a long time and many emails working towards our conclusion that a cellular component is an anatomical structure. We're not changing that aspect of it now (and it works fine for cellular component morphogenesis is_a anatomical structure morphogenesis), so the question is just about assembly versus formation.
There's some cleanup to do generally for cell projection terms. I think this was sort of on our radar but hasn't been done yet. We have both "cell projection morphogenesis" and "cell projection assembly", but most cell projections only have an assembly term, and there's some parentage inconsistency.
m
Original comment by: mah11
The problem seemd to be that "cellualr componet assembly" isn't an "anatomical structure formation" in the context that a developmental biologist would thnk of "formation" but the scope has been broadened so much as to include cellular component assembly.
I can see that some cellualr componets can be considered anatomical, but not all complexes. (all of protein complex assembly is under here)
If the def of formation was tightened back to its "developmental" context (how jen described it to me, it is the initial stages of a bud or limb forming), couldnt:
i) the relationship between cellular componet asembly and anotomical structure formation be removed and ii) anatomical strucure formation go back under development?
This was the conclusion we came to during slimming club, Or are we overlooking something obvious?
It just seems to be a big "mixed bag" of stuff under here (i.e. it wouldn't be a very biologically meaningful term in the slim)
Original comment by: ValWood
I think we need to keep two things in mind here.
1) The cell is a cellular component and every cellular component is an anatomical structure. So anything that is happening to a cellular component is happening to an anatomical structure.
2) Development is the progression of something over time.
So if something is being assembled as a part of the progression of that thing from an immature state to a mature state, then assembly is a type of formation in the developmental sense and that is in turn a part of morphogenesis.
David
Original comment by: ukemi
In light of the work we did earlier and David's comments here and on the ATPase SF item, I think there's no problem with the high-level terms. The only thing that really needs fixing is the inconsistency in the cell projection assembly/formation terms.
m
Original comment by: mah11
Jane has made the generic 'anatomical structure formation' obsolete (SF 2916324), and David has cleaned up the cell projection assembly/formation terms (SF 2015221), so I think the name, definition, and ancestry of 'mating projection assembly' make sense.
m
https://sourceforge.net/tracker/?func=detail&atid=440764&aid=2015221&group\_id=36855 https://sourceforge.net/tracker/?func=detail&atid=440764&aid=2916324&group\_id=36855
Original comment by: mah11
Original comment by: mah11
Original comment by: mah11
mating projection assembly peptide mating pheromone maturation involved in pheromone-induced unidirectional conjugation
this seems an odd name and def for this process.
The mating projection forms, as far as I know by moement of the underlying cytoskelelton etc and isn't reallt "assembly" as defined here (its usually referred to as "formation".
Perhaps if the term was renamed "mating projection morphogenesis" and redefined (to match its morophogenesis parent, and the parentage to "cell projection asembly" was removed, this would work better.
Actually, as Jane, jen and I were discussing recently, cellular componet assembly under anotomical structure formation seems wrong. I have a problem from a unicellular persepctive, and jen thinks this changes the meaning of "formation" in development.
Reported by: ValWood
Original Ticket: geneontology/ontology-requests/6802