Closed gocentral closed 9 years ago
Original comment by: jl242
Original comment by: jl242
Logged In: YES user_id=735846
Hi Val, If you think that the definition of chromatin remodeling complex and GO:0016585, and chromatin silencing complex ; GO:0005677 is probably the same then does that mean that you have some specific definition in mind? It would help me a lot if you could let me know what that is.
Thanks,
Jen
Original comment by: jenclark
Logged In: YES user_id=516865
This may be OK...I'm just not sure. are all of the child complexes part of one big "chromatin remodelling complex? " or should the individual complexes just be annotated to nucleoplasm?
Original comment by: ValWood
Logged In: YES user_id=735846
added:
COMPASS complex ; GO:0048188 def: The COMPASS complex (Complex Proteins Associated with Set1) consists of seven polypeptides, ranging from 130 to 25 kDa, and is related to the trithorax complexes. PMID:11687631
Lid2 complex ; GO:0048189 def: A complex containing Lid2; a protein that contains three PHD fingers, a BRIGHT domain, and a JmjC domain. The BRIGHT domain is a helix-turn-helix DNA binding domain with preference for AT-rich regions. The domain has no known function but may be involved in regulation of chromatin remodeling. PMID:12488447
is_a children of chromatin remodeling complex ; GO:0016585
Original comment by: jenclark
Original comment by: jenclark
Logged In: YES user_id=436423
I have rewritten the definitions for these -- better wordings, and a bit of newer information for compass.
m
Original comment by: mah11
Original comment by: mah11
add (as child of chromatin remodeling complex ; GO:0016585, OR chromatin silencing complex ; GO:0005677 or both)...actually if these are defined they may be the same term?)
refs PMID:12488447 PMID: 11687631 PMID: 11752412 PMID: 11742990 Appears to be conserved in all eukaryotes
There is also an additional complex in S. pombe called Lid2 which interacts physically with SET1 and is absent from S. cerevisiae PMID:12488447
Reported by: ValWood
Original Ticket: "geneontology/ontology-requests/628":https://sourceforge.net/p/geneontology/ontology-requests/628