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geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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mRNA destabilization terms #7692

Closed gocentral closed 9 years ago

gocentral commented 14 years ago

Hi,

Can you add the term:

GONEW: mRNA destabilization, as a child term for "GO:50779 RNA destabilization"

Def: Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. (this is modified from the def for GO:50779 RNA destabilization.)

and then add a child term for mRNA destabilization: GONEW: 3'-UTR-mediated mRNA destabilization

Def: An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.

Reference: PMID: 14570877 SGD: jh

Thanks, Jodi

Reported by: jodih

Original Ticket: geneontology/ontology-requests/7474

gocentral commented 14 years ago

mRNA destabilization ; GO:0061157 3'-UTR-mediated mRNA destabilization ; GO:0061158

Original comment by: ukemi

gocentral commented 14 years ago

Original comment by: ukemi