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Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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ubiquitin thioloesterase/ ubiquitin protease #7989

Closed gocentral closed 9 years ago

gocentral commented 14 years ago

I knoe this has come up before, but after reading the definitions, exact synonyms and comments for ubiquitin thiolesterase activity and ubiquitin-specific protease activity I can't work ot why ubiquitin-specific protease activity is not a child of ubiquitin thiolesterase activity

Reported by: ValWood

Original Ticket: geneontology/ontology-requests/7774

gocentral commented 14 years ago

Actually I see, but i am trying to annotate

Ubiquitin carboxyl-terminal hydrolases.

It isn't clear to me which of these tems I should use. If I used the common partent I would have to use "hydrolase" activity

Original comment by: ValWood

gocentral commented 14 years ago

Original comment by: ValWood

gocentral commented 14 years ago

aha - EC says ubiquitin carboxyl-terminal hydrolase = ubiquitin thiolesterase

http://www.chem.qmul.ac.uk/iubmb/enzyme/EC3/0102.html\#15

and GO has the synonym

Original comment by: mah11

gocentral commented 14 years ago

but it is also a ubiquitin protease, see abstract PMID: 20838651 so there isn't a term to capture both

Original comment by: ValWood

gocentral commented 14 years ago

so do you want a new term, or can you just annotate to both existing terms?

Original comment by: mah11

gocentral commented 14 years ago

ideally there would be a single term as its one function, but i already annotated to both so its fine.

If there is any confusion later I can re open.....

Original comment by: ValWood

gocentral commented 14 years ago

OK, I'll close this, but reopen if you change your mind

Original comment by: mah11

gocentral commented 14 years ago

Original comment by: mah11

gocentral commented 13 years ago

Original comment by: mah11