geneontology / go-ontology

Source ontology files for the Gene Ontology
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MP of translesion synthesis and has_part #7997

Closed gocentral closed 9 years ago

gocentral commented 14 years ago

The term GO:0019985 translesion synthesis The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide

is not longer a part of child to DNA replication although DNA replication has a has_part relation to DNA biosynthetic process.

I don't really understand the has_part relationship I now realise, so this might be why, but I don't see why the old relationship no longer exists heres. In fact in Quickgo it seems as though the arrows are pointing the wrong way, we have DNA replication has_part DNA biosynthetic process and I know that this should be the other way around, maybe that is wy I am confused.... check this out

http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0019985

and "ancestor view"

I think we probably need some sort of tutorail for has_part and how it is used.....

Val

Reported by: ValWood

Original Ticket: geneontology/ontology-requests/7782

gocentral commented 14 years ago

Midori, please do not despair. I understand totally why translesion synthesis etc are not part of DNA replication. I just read your lovely new defs and it all makes sense.

Now I just need to understand has_aprt and all will be fine......

Original comment by: ValWood

gocentral commented 14 years ago

Sorry, I really don't get it at all.

I don't know why DNA biosynthestic process is not a parent of DNA replication?

Is this obvious?

Original comment by: ValWood

gocentral commented 14 years ago

"DNA replication has_part DNA biosynthetic process" is the right way round, and we haven't used is_a or part_of, because ...

- not all DNA synthesis takes place as part of replication; sometimes it's part of repair

- DNA replication always involves synthesis of DNA, but also involves other parts (e.g. RNA primer synthesis, ORC or analogous complex assembly at origins, etc., etc.)

Does that help at all? m

Original comment by: mah11

gocentral commented 14 years ago

Yes it makes sense when it's written like that. I think I ham having problems interpreting the relationship in the graph.....Its so odd to have a relationship where the annotations do not propagate that I am finding it difficult to figure out the relationship with between the annotations and the terms. Hopefully I will get there soon....

Original comment by: ValWood

gocentral commented 14 years ago

Do we need to do anything for this item? m

Original comment by: mah11

gocentral commented 14 years ago

nope. User error.

Original comment by: ValWood

gocentral commented 14 years ago

ok, closing

Original comment by: mah11

gocentral commented 14 years ago

Original comment by: mah11

gocentral commented 13 years ago

Original comment by: mah11