gocentral
commented
14 years ago At the moment we have nuage as a broad synonym for P granule:
[Term] id: GO:0043186 name: P granule namespace: cellular_component alt_id: GO:0018994 def: "A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes." [GOC:dph, GOC:kmv, PMID:11262230] synonym: "germline granule" EXACT [] synonym: "nuage" BROAD [] synonym: "polar granule" EXACT [] is_a: GO:0043232 ! intracellular non-membrane-bounded organelle is_a: GO:0044444 ! cytoplasmic part relationship: part_of GO:0060293 ! germ plasm
Should we change this, or will it suffice for you?
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Original comment by: mah11
According to FBrf0155724 == Findley et al., 2003
A conserved feature of germ cells in species across the animal kingdom is the presence of a distinct morphological element called nuage. Ultrastructurally, nuage appears as electron-dense granules that are localized to the cytoplasmic face of the nuclear envelope (reviewed by Eddy, 1975; Saffman and Lasko, 1999).
Potentially useful refs:
Eddy, E. M. (1975). Germ plasm and the differentiation of the germ line. Int. Rev. Cytol. 43, 229-281 Germline development in vertebrates and invertebrates. FBrf0110704 == Saffman and Lasko, 1999, Cell. Molec. Life Sci. 55(8-9): 1141--1163 "Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster." FBrf0200142 == Lim and Kai, 2007, Proc. Natl. Acad. Sci. U.S.A. 104(16): 6714--6719 "Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage." FBrf0155724 == Findley et al., 2003, Development 130(5): 859--871
Reported by: dosumis
Original Ticket: geneontology/ontology-requests/7901