Closed gocentral closed 9 years ago
Can't do is_a or part of with either suggested parent
- you're right about why not RNA processing: the snoRNP assembly is upstream.
- box H/ACA snoRNPs catalyze pseudouridylation, and their targets include at least one spliceosomal RNA (U2) as well as rRNA.
as far as I can tell, it wouldn't be wrong to say ribosome biogenesis has_part box H/ACA snoRNP assembly ... but then do we want to do the same for assembly of any other complex involved in rRNA cleavage, modification, etc.?
m
Original comment by: mah11
p.s. meant to include some PMIDs, then hit 'update' too soon ...
12515384, 15199136, 12409454
Original comment by: mah11
extra fun: apparently the RNPs that pseudouridylate spliceosomal RNAs are in the Cajal body (and have a slightly different name) in bigger eukaryotes, but that doesn't help wint parentage for the assembly term because the TPV risk is still there for yeasties.
Original comment by: mah11
Original comment by: mah11
Original comment by: paolaroncaglia
Original comment by: paolaroncaglia
Hi Midori and Val,
Going through old open/unassigned SF requests. Based on Midori's comments, which make sense to me, I think that this request can be closed. But if you think otherwise and have more suggestions on how to deal with this, please feel free to comment and open again.
Thanks, Paola
Original comment by: paolaroncaglia
Original comment by: paolaroncaglia
box H/ACA snoRNP assembly (GO:0000493) is defined The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
At SGD genes involve din this porcess are defined as: Chaperone protein required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing,
Therefore, should this term have the parent rRNA processing (probably not because this process is upstream of rRNA processing) OR, should have the parent
ribosome biogenesis, A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
which appears broad enough to include assembly of box H/ACA snoRNPs
val.
Reported by: ValWood
Original Ticket: geneontology/ontology-requests/8082