ecdysteroid 22/2 hydroxylase

[gocentral]

Please can i have 2 new function terms as children of both steroid hydroxylase activity ; GO:0008395 and cytochrome P450 activity ; GO:0015034

term: ecdysteroid 22-hydroxylase activity def: Catalysis of the hydroxylation of an ecdysteroid at carbon position 22. comment: In the ecdysteroidogenic pathway, this activity catalyses the conversion of 2,22-dideoxyecdysone (ketotriol) to 2-deoxyecdysone.

term: ecdysteroid 2-hydroxylase activity def: Catalysis of the hydroxylation of an ecdysteroid at carbon position 2. comment: In the ecdysteroidogenic pathway, this activity catalyses the conversion of 2-deoxyecdysone to ecdysone. It can also catalyse the conversion of 2,22-dideoxyecdysone (ketotriol) to 22-deoxyecdysone.

Ref:12177427. Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster.

Thanks,

Becky

Reported by: beckyfoulger

Original Ticket: "geneontology/ontology-requests/853":https://sourceforge.net/p/geneontology/ontology-requests/853

[gocentral]

• milestone: --> TermGenie
• assigned_to: nobody --> jl242

Original comment by: jl242

[gocentral]

Logged In: YES user_id=451873

Both seem fine - will add on Friday if no further comments.

Original comment by: jl242

[gocentral]

Logged In: YES user_id=451873

Added 'ecdysteroid 2-hydroxylase activity ; GO:0042768' and ' ecdysteroid 22-hydroxylase activity ; GO:0042767' as described above.

Original comment by: jl242

[gocentral]

• status: open --> closed-accepted

Original comment by: jl242