EASY: hepacyte growth factor biosynthesis

[gocentral]

Hi,

For annotation of P09529,

pubmed 121419948

I need new term: 'hepacyte growth factor biosynthesis' and its regulation terms as a child of 'cytokine biosynthesis'

cheers Evelyn

Reported by: ecamon

Original Ticket: "geneontology/ontology-requests/910":https://sourceforge.net/p/geneontology/ontology-requests/910

[gocentral]

• milestone: --> TermGenie
• assigned_to: nobody --> jenclark

Original comment by: jenclark

[gocentral]

Logged In: YES user_id=735846

Hiya,

I think this must be about hepatocytes since I can't find hepacytes anywhere. I have put together the following terms to be committed fairly soon if no one objects:

cytokine biosynthesis ; GO:0042089 --%hepatocyte growth factor biosynthesis ; GO:new ----<regulation of hepatocyte growth factor biosynthesis ; GO:new ------<positive regulation of hepatocyte growth factor biosynthesis ; GO:new ------<negative regulation of hepatocyte growth factor biosynthesis ; GO:new

cytokine biosynthesis ; GO:0042089

def: The formation from simpler components of cytokines, any of a group of proteins that are released by mammalian cells and which have autocrine and paracrine activity.

hepatocyte growth factor biosynthesis ; GO:new def: The formation from simpler components of hepacyte growth factor. Hepatocyte growth factor is a mitogen for a number of cell types and it is found in liver cells and in many other cell types, including platelets. synonym: scatter factor biosynthesis, HGF biosynthesis http://cancerweb.ncl.ac.uk

regulation of hepacyte growth factor biosynthesis ; GO:new def: Any process that modulates the frequency, rate or extent of the formation from simpler components of hepacyte growth factor. synonym: regulation of scatter factor biosynthesis, regulation of HGF biosynthesis http://cancerweb.ncl.ac.uk

positive regulation of hepacyte growth factor biosynthesis ; GO:new def: Any process that activates or increases the rate of the formation from simpler components of hepacyte growth factor. synonym: positive regulation of scatter factor biosynthesis, positive regulation of HGF biosynthesis http://cancerweb.ncl.ac.uk

negative regulation of hepacyte growth factor biosynthesis ; GO:new def: Any process that stops, prevents or reduces the rate of the formation from simpler components of hepacyte growth factor. synonym: negative regulation of scatter factor biosynthesis, negative regulation of HGF biosynthesis http://cancerweb.ncl.ac.uk

Original comment by: jenclark

[gocentral]

Logged In: YES user_id=735846

I have added these terms:

cytokine biosynthesis ; GO:0042089 --%hepatocyte growth factor biosynthesis ; GO:new GO:0048175 ----<regulation of hepatocyte growth factor biosynthesis ; GO:new GO:0048176 ------<positive regulation of hepatocyte growth factor biosynthesis ; GO:new GO:0048177 ------<negative regulation of hepatocyte growth factor biosynthesis ; GO:new GO:0048178

hepatocyte growth factor biosynthesis ; GO:new def: The formation from simpler components of hepacyte growth factor. Hepatocyte growth factor is a mitogen for a number of cell types and it is found in liver cells and in many other cell types, including platelets. synonym: scatter factor biosynthesis, HGF biosynthesis http://cancerweb.ncl.ac.uk

regulation of hepacyte growth factor biosynthesis ; GO:new def: Any process that modulates the frequency, rate or extent of the formation from simpler components of hepacyte growth factor. synonym: regulation of scatter factor biosynthesis, regulation of HGF biosynthesis http://cancerweb.ncl.ac.uk

positive regulation of hepacyte growth factor biosynthesis ; GO:new def: Any process that activates or increases the rate of the formation from simpler components of hepacyte growth factor. synonym: positive regulation of scatter factor biosynthesis, positive regulation of HGF biosynthesis http://cancerweb.ncl.ac.uk

negative regulation of hepacyte growth factor biosynthesis ; GO:new def: Any process that stops, prevents or reduces the rate of the formation from simpler components of hepacyte growth factor. synonym: negative regulation of scatter factor biosynthesis, negative regulation of HGF biosynthesis http://cancerweb.ncl.ac.uk

Original comment by: jenclark

[gocentral]

• status: open --> closed-fixed

Original comment by: jenclark