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geneontology / go-ontology

Source ontology files for the Gene Ontology
http://geneontology.org/page/download-ontology
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CatSper complex #9437

Closed gocentral closed 9 years ago

gocentral commented 12 years ago

Category: Component

Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization.

PubMed=21224844;

child of GO:0005891 voltage-gated calcium channel complex

Reported by: sylvainpoux

Original Ticket: geneontology/ontology-requests/9228

gocentral commented 12 years ago

Original comment by: rebeccafoulger

gocentral commented 12 years ago

Hi Sylvain,

Added in: [Term] id: GO:0036128 name: CatSper complex namespace: cellular_component def: "A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits." [GOC:sp, PMID:17478420, PMID:21224844, PMID:22354039] synonym: "CATSPER channel" EXACT [PMID:21224844] synonym: "CatSper channel complex" EXACT [PMID:17478420] is_a: GO:0005891 ! voltage-gated calcium channel complex created_by: rfoulger creation_date: 2012-03-02T10:26:48Z

thanks, Becky

Original comment by: rebeccafoulger

gocentral commented 12 years ago

Original comment by: rebeccafoulger