NTR: RNA-directed DNA methylation

[gocentral]

RNA-directed DNA methylation Synonym exact: RdDM

Biological Process

Def: An epigenetic RNA-based gene silencing process first elucidated in plants whereby 24-nt small interfering RNAs (siRNAs) guide DNA methyltransferases to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci.

PMID:21420348

Is_a GO:0031047 : gene silencing by RNA

Reported by: donghui

Original Ticket: geneontology/ontology-requests/9266

[gocentral]

added GO:0080188

Original comment by: donghui

[gocentral]

• status: open --> closed-accepted

Original comment by: donghui