geneontology / go-releases

Tasks and notes for monthly GO releases
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UniProt loosing many IEAS #78

Closed pgaudet closed 2 months ago

pgaudet commented 3 months ago

UniProt lost -66583 annotations, ie -7.47%

Looks like this is due to remove KW mappings.

pgaudet commented 2 months ago

From Alex: this is expected, as the KW script is now removing redundant predictions (ie GO annotations made to a term and one or more of its ancestors; only the annotation to the most specific term is kept).

pgaudet commented 2 months ago

Weirdly, not all organisms are equally affected. I expected the organisms for which the source of IEAs is directly GOA to all drop: human, Danio, Drosophila, and E. coli.

TAXON | ALL | IEA -- | -- | -- NCBITaxon:9606\|Homo sapiens | -5380 | -8313 NCBITaxon:10116\|Rattus norvegicus | -4231 | -6446 NCBITaxon:10090\|Mus musculus | -2979 | -6716 NCBITaxon:3702\|Arabidopsis thaliana | 241 | -19 NCBITaxon:7955\|Danio rerio | 566 | -1019 NCBITaxon:6239\|Caenorhabditis elegans | 1516 | 641 NCBITaxon:559292\|Saccharomyces cerevisiae S288C | -5093 | -6019 NCBITaxon:7227\|Drosophila melanogaster | -2708 | -183 NCBITaxon:44689\|Dictyostelium discoideum | -6987 | -7287 NCBITaxon:4896\|Schizosaccharomyces pombe | 1517 | 1322 NCBITaxon:83333\|Escherichia coli K-12 | -82 | -192