Can MFs be 'part of' other MFs?

[vanaukenk]

Looking at annotation extensions for MF annotations, curators have made 'part of' relations between MFs. These annotations have also been made in GO-CAM models.

Do we want to allow this?

If so, we need to add it to the ShEx specs.

[balhoff]

@vanaukenk did this come up in the call yesterday? I can't remember.

[vanaukenk]

No, we didn't discuss this on yesterday's call.

@thomaspd @pgaudet What do we want to do wrt annotating sub-functions in GO-CAM models?

[ukemi]

For compound functions, this will be required won't it?

[vanaukenk]

@ukemi - I would think so, yes.

We could have one 'main function' and then have 'has part' relations from that to the sub-functions.

[ukemi]

But at the instance-level has_part and part_of are inverse properties.

[vanaukenk]

Further discussion with @balhoff and @ukemi

Adding a 'has part' @\ *;

should suffice to capture sub-functions, if we want to do that from a curation pov.

[vanaukenk]

A related issue for this is whether or not we want to annotate where sub-functions occur in GO-CAM models, e.g. ligand binding 'occurs in' extracellular region'.

[ukemi]

We should explore this. It might solve some spatial issues that have crept up recently.

[balhoff]

@vanaukenk:

Adding a 'has part' @<MolecularEntity> *;

I think you meant MolecularFunction?

[vanaukenk]

@balhoff - Yes, I've updated the original comment. Thx.

[pgaudet]

@thomaspd @cmungall : Yes

[vanaukenk]

ShEx still needs to be updated here.