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The Gene Ontology Helpdesk
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Confused by GO:0061990, molecular_function "beta-ketodecanoyl-[acyl-carrier-protein] synthase" #103

Closed baoilleach closed 6 years ago

baoilleach commented 6 years ago

For the most part, molecular functions appear to avoid colliding with names of proteins, sometimes by appending the term "activity". However, there are a number of terms whose names are synthases rather than "synthase activity". For example...

GO:0061990 has the name beta-ketodecanoyl-[acyl-carrier-protein] synthase

But Uniprot Q9HYV7 (http://www.uniprot.org/uniprot/Q9HYV7) is named "Beta-ketodecanoyl-[acyl-carrier-protein] synthase". It even is annotated with GO terms, none of which is GO:0061990. It also has a Wikipedia page (https://en.wikipedia.org/wiki/Beta-ketodecanoyl-(acyl-carrier-protein)_synthase).

In short, is this an error in GO, or have I made an error?

kltm commented 6 years ago

@ukemi @vanaukenk

Would either of you know the right person to contact internally to answer this question?

ukemi commented 6 years ago

Hi @kltm

The term name is incorrect. I should have added activity for exactly the reason mentioned above. I will do that now. @vanaukenk , the experimental annotations that exist for the protein are derived from the publication on the wikipedia page. Can you arrange to have them reviewed?

suzialeksander commented 6 years ago

@sandyl27 , has this issue been resolved? I see the term name for GO:0061990 has been fixed, but I don't see any annotations to this term. Can you review the protein mentioned? Thanks

sandyl27 commented 6 years ago

I have looked at the annotations in CACAO and have fixed them.

suzialeksander commented 6 years ago

@baoilleach, I think we've resolved this issue. Thank you for bringing it to our attention! If there are any more errors or questions, please open a new ticket.