Intracellular metabolism of fatty acids regulates insulin secretion (R-HSA-434313)

[ukemi]

• [x] make mouse model
  • [x] gomodel:62f58d8800004224
• [ ] Right now the Reactome pathway is two steps, but there is lots more downstream that is already captured in Reactome, eg beta oxidation of fatty acids. Do we want to try to connect it all up?
• [ ] PMID:33398164 gives a very different mechanism of FFA control of insulin secretion than PMID:29565831. Do we know the latest thoughts? The general consensus is that palmitate doesn't stimulate insulin secretion, but rather induces apoptosis of beta cells.