genepi / imputationserver2

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More than 100 allele switches have been detected. Imputation cannot be started! #34

Closed Adeel3Dgenomics closed 1 month ago

Adeel3Dgenomics commented 1 month ago

Hi all,

i am trying to impute a sample data set, and it continuously giving me this error. i have my_study.bim, .bed and .fam

"More than 100 allele switches have been detected. Imputation cannot be started!"

data preparation commands are as follows.

plink --freq --bfile my_study --out my_study perl HRC-1000G-check-bim.pl -b my_study.bim -f my_study.frq -r HRC.r1-1.GRCh37.wgs.mac5.sites.tab -h sh Run-plink.sh plink --bfile my_study-updated-chr3 --recode vcf --out my_study_chr3 vcf-sort my_study-chr3.vcf| bgzip -c > my_study-chr3.vcf.gz