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genetics-statistics / GEMMA

Genome-wide Efficient Mixed Model Association
https://github.com/genetics-statistics/GEMMA
GNU General Public License v3.0
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Major allelle influences additive effect sign #240

Open pjotrp opened 3 years ago

pjotrp commented 3 years ago

We just hit this issue by providing additive effect in GeneNetwork. The sign is wrong when major allele is entered wrong in the BIMBAM file. GEMMA should really compute major allele rather than assume it was entered correctly.