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genetics-statistics / GEMMA

Genome-wide Efficient Mixed Model Association
https://github.com/genetics-statistics/GEMMA
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GSL ERROR: matrix is singular in lu.c at line 147 errno 1 #249

Open AgatheMaupetit opened 3 years ago

AgatheMaupetit commented 3 years ago

Hi !

Running a multivariate model with gemma 0.98.4: gemma -bfile $DATAWORK/genot -k $DATAWORK/K_Plim.txt -lmm 4 -n 12 41 -o mlmm_2traits I get this wellknown error: GSL ERROR: matrix is singular in lu.c at line 147 errno 1

But I do not get it using only one trait. So there is no issue with the data files.

I have 100 individuals and 98031 SNPs analyzed. Traits have a normal distribution and are not correlated as suggested in other issues.

Here is the output :

image

Do you have any idea to solve this problem ?

Thank you in advance for your help.

Agathe

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