genetics-statistics / GEMMA

Genome-wide Efficient Mixed Model Association
https://github.com/genetics-statistics/GEMMA
GNU General Public License v3.0
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Gemma run-time for Estimate Relatedness Matrix calculation #265

Open alviitayyaba opened 2 years ago

alviitayyaba commented 2 years ago

Hi, I am new to GWAS. I have dataset of 15K+ individuals and 200+ SNPs. I wanted to estimate the relatedness matrix, I used the following command.

gemma -bfile data_QC -gk 1 -o data_QC_gem

GEMMA 0.98.3 (2020-11-28) by Xiang Zhou and team (C) 2012-2020 Reading Files ...

number of total individuals = 15628

number of analyzed individuals = 2904

number of covariates = 1

number of phenotypes = 1

number of total SNPs/var = 270047

number of analyzed SNPs = 260663

Calculating Relatedness Matrix ... ======= 15%

It's been running for 4+ hours. How much time it will take to complete? Does it depend on computational resources on my machine? Any help in this regard would be appreciated. Thank you