Pindel can detect breakpoints of large deletions, medium sized insertions, inversions, tandem duplications and other structural variants at single-based resolution from next-gen sequence data. It uses a pattern growth approach to identify the breakpoints of these variants from paired-end short reads.
I only want to know which signals used Pindel to detect variants. The main signal is split read, but now I found a paper where they mention the usability of Discordant Reads too... So I will appreciate inform which strategies use Pindel in order to detect variants.
Dear all,
I only want to know which signals used Pindel to detect variants. The main signal is split read, but now I found a paper where they mention the usability of Discordant Reads too... So I will appreciate inform which strategies use Pindel in order to detect variants.
Thanks for your time
Jordi