search

gerlichlab / looptrace

Fork (from EMBL Gitlab) of the looptrace project: https://git.embl.de/grp-ellenberg/looptrace
MIT License
2 stars 1 forks source link

We should be able to compute distances between regional spot centroids, too #199

Closed vreuter closed 5 months ago

vreuter commented 6 months ago

Right now, we compute distances between centroids of pairs of locus-specific FISH spots, but not of regional ones. For new work by @TLSteinacker , we'd like to also compute distances between centroids of the regional barcode spots. This should require just adapting from which columns we pull the necessary grouping and spatial information, pulling now from the filtered spots file rather than from the QC'd trace supports file.

vreuter commented 6 months ago

Related to #191, where we'll bring the pairwise distance computation logic into this project, so we should wait for resolution of that ticket and then adapt the distance computation code to be able to handle both the regional and locus-specific pairwise distances computation.