how to use this tool to create coverage file required by mutsigcv ?

getzlab / mutsig_covgen

Generate coverage models for MutSig2CV/NC

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how to use this tool to create coverage file required by mutsigcv ? #1

Open stroke1989 opened 2 years ago

stroke1989 commented 2 years ago

Excuse me: could you make a example of how to to use this tool to create coverage file required by mutsigcv? this tool required a input file with wig format, how to create a wig format input file? Hope your response! Appreciate! Best wishes for you during the worldwide pandemic.

julianhess commented 2 years ago

This tool is designed to be run on WIGs generated by MuTect. MuTect will automatically generate a coverage WIG for each tumor/normal pair it is run on. This tool can then aggregate those into a MutSig coverage model.