gexijin / idepGolem

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Download the enriched pathways with up and down regulated genes separated #567

Open JianYes opened 11 months ago

JianYes commented 11 months ago

Is your feature request related to a problem? What value do you see this adding? Please describe. For Pathway tab, we need to add download option of the enriched pathways with the normal information such as group, FDR, nGenes, Pathway size, Fold enrichment, Pathway, URL and Genes. It's better to separate the up and down regulated genes in different columns.

Describe the solution you'd like The table may include group, FDR, nGenes, Pathway size, Fold enrichment, Pathway, URL, GenesUp, and GenesDown.

Describe alternatives you've considered One user suggested to add the columns of number of up regulated genes and down regulated genes. We may express nGenes with two columns as nGenesUp, nGenesDown if it's necessary.

Additional context At least, we need the option to download the enriched pathways with normal information if we don't separate the genes into up and down.

ChrisTret commented 8 months ago

Hey Jenny, I just want to make sure I am understanding what is wanted. Here is what the current csv looks like and also a what I imagine we want the "new" csv to look like. Is this what you are picturing. Some of it is just dummy data. new.csv sig_pathways.csv

JianYes commented 8 months ago

Not really, Chris. Right now in these two files we only list the total gene number in the column "Genes" for the enriched pathways. Actually, for each pathway, we define it as up(or down) when most of the genes included in this pathway are up(or down), not all of the genes are up(or down). The user tried to know how many genes are up and how many are down for each enriched pathway, if it's possible.

JianYes commented 4 months ago

For the downloaded csv file of the pathway enrichment, at least we need to include the regulated genes! Just like the one in DEG2, which including group, FDR, nGenes, Pathway size, Fold enrichment, Pathway, URL, and Genes.

gexijin commented 4 months ago

List of genes in pathway analysis results.