Closed biethbr1 closed 1 year ago
All shrinkage labels for ggPMX plots use shrinkage that is computed based on SD.
However, Novartis PMX Internal Guidance for model building, evaluation, and qualification recommended the use of shrinkage that is based on variance.
Monolix2018 with the following example:
mlxtran_file = "/USER_EXAMPLES/MLX/2018/8.PKPD/SIMULTANEOUS_USING_LIBRARIES/warfarin_PKPDlibrary_project.mlxtran" ctr = pmx_mlxtran(file_name = mlxtran_file, endpoint = "2")
For example:
(Old Ticket #220)
ok, works.
All shrinkage labels for ggPMX plots use shrinkage that is computed based on SD.
However, Novartis PMX Internal Guidance for model building, evaluation, and qualification recommended the use of shrinkage that is based on variance.
Test case:
Monolix2018 with the following example:
For example:
(Old Ticket #220)