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gkichaev / PAINTOR_V3.0

Fast, integrative fine mapping with functional data
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how to getZ-scores #13

Closed lantianbaiyunrui closed 7 years ago

lantianbaiyunrui commented 7 years ago

Hi, I am appreciated using this software to complete my program. However, my gwas data does not include Z-scores, may I convert P-value to Z-scores, using this formula (p-mean(p))/sd(p), could you give me some suggestions. Thank you very much! All best! rui

gkichaev commented 7 years ago

Hi Rui,

I'm not sure what p in your formula represents? Is that the p-value? I'm not familiar with that transformation.

What you could do is invert the p-value to Zscore using the "qnorm" command in R. However, you will need the sign of the Z-scores. If those are unavailable to you, then you will not be able to run the software.

Gleb

lantianbaiyunrui commented 7 years ago

hi gkichaev, thank you for your response, I can try it 1