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Evaluate GlycoGPT #1092

Open ReneRanzinger opened 4 months ago

ReneRanzinger commented 4 months ago

Hi,

one of the things we did not put into the grant application was the idea of having a chatbot for GlyGen.org. Mainly because it was complicated at that time.

With the recently introduced GPTs and the GPTstore we may want to rethink that. We could train a general purpose GPT with the essentials book and get a reasonable GlycoGPT. We could also use text synthesis to convert GlyGen data into training text for GPT.

e.g., The name for P14210-1 is HGF. HGF is a human protein. HGF function is Cancer-Associated Fibroblasts Promote Radioresistance of Breast Cancer Cells via the HGF/c-Met Signaling Pathway. HGF binds glycan G19059PI.

Maybe a project for a student to test it out and play around with. However, to make an own GPT you need a paid OpenAI account.

Best, René

ReneRanzinger commented 4 months ago

We might have to seek permission to use “essentials” but I like this idea. Especially if we can prime it with ways to navigate or deep link to specific items.

Are there examples of this applied to a scientific data website elsewhere?

ReneRanzinger commented 4 months ago

@ReneRanzinger and @mtiemeyer0919 will look into finding an RA student to look into this.

ReneRanzinger commented 3 months ago

@edwardsnj @sujeetvkulkarni

If I supervised a ChatGPT chat-bot transfer learning internship project with respect to GlyGen and glycosylation along the lines of your suggestion a few weeks ago?

I consider this your idea (so you have veto here), but I'm sure if I suggest this to our (bioinformatics) students, at least one will be interested enough in it to do it. So I won't suggest it unless you are OK with it.

Perhaps you might want to co-mentor (informally)? The internship would run over the summer, we could Zoom with you once a week?!?!?!

I should be able to get some funding to pay for the OpenAI fees.

Cheers!