Closed kmartinez834 closed 5 months ago
@rykahsay We need to map biomarker id's to motif id's. Will this require a dataset change, or can you add directly to the API? FYI, I'm assigning this to 2.5
glycan_biomarkers.csv
"glytoucan_ac","biomarker_id"
glycan_biomarkers.csv
"glytoucan_ac","motif_ac"
👉 Use "glytoucan_ac"
to map "biomarker_id"
to "motif_ac"
Ex. A0485 --> G28790AT --> GGM.000001, GGM.000005, GGM.000034
Ex. Add same info present in https://api.glygen.org/glycan/detail/G28790AT "biomarkers"
section to all mapped motif APIs (GGM.000001, GGM.000005, GGM.000034)
{
"biomarkers": [
{
"assessed_biomarker_entity": "Disialylated tetraantennary core fucosylated N-glycan",
"biomarker_id": "A0485",
"evidence": [
{
"id": "GLY_000737",
"database": "GlyGen",
"url": "https://data.glygen.org/GLY_000737"
},
{
"id": "18487288",
"database": "PubMed",
"url": "https://glygen.org/publication/PubMed/18487288"
}
],
"instances": [
{
"best_biomarker_type": "diagnostic",
"status": "increased disialylated tetraantennary core fucosylated N-glycan level",
"disease": {
"disease_id": "DOID:1612",
"recommended_name": {
"id": "DOID:1612",
"resource": "Disease Ontology",
"url": "http://disease-ontology.org/term/DOID:1612",
"name": "breast cancer",
"description": "A thoracic cancer that originates in the mammary gland."
},
"synonyms": [
{
"id": "DOID:1612",
"resource": "Disease Ontology",
"url": "http://disease-ontology.org/term/DOID:1612",
"name": "breast tumor"
},
]
},
"tissue": {
"name": "blood",
"namespace": "UBERON",
"id": "0000178",
"url": "http://purl.obolibrary.org/obo/UBERON_0000178"
},
"evidence": [
{
"id": "GLY_000737",
"database": "GlyGen",
"url": "https://data.glygen.org/GLY_000737"
},
{
"id": "18487288",
"database": "PubMed",
"url": "https://glygen.org/publication/PubMed/18487288"
}
]
}
]
}
]
}
Who decided to propagate biomarker knowledge from glycan to associated motif(s)?
Closing this ticket. Per Dev meeting on 5/22, motif page biomarkers must be associated with that motif's GlyTouCan accession.
https://tst.glygen.org/biomarker/A0485 https://tst.glygen.org/glycan/G28790AT#Motifs
https://tst.glygen.org/motif/GGM.000001#Biomarkers